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Injection Lipolysis

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Injection Lipolysis

Liposuction to remove subcutaneous fat is one of the most common aesthetic surgical procedures. However, liposuction is a surgical procedure and often requires general anesthesia, and has the potential for medical complications. Therefore, there has always been a beeline for something non-surgical which can provide the same level of improvement as liposuction does. Unfortunately, no non-surgical procedure has even reached 30-40 % of an outcome following Liposuction. Injection Lipolysis is the only procedure which has consistently shown through documentation, reduction of small fat deposits permanently.

The use of lipolytic drugs to induce a nonsurgical fat reduction is a common method in cosmetic medicine, either through topical treatments (creams, fluids) or through local injections, particularly for people seeking non-surgical options only as well as areas that may not be amenable to liposuction.

Subcutaneous injection of phosphatidylcholine (PC) solubilized in deoxycholate (DC) has been purported to eliminate body fat by fat cell lysis the outcome of which is essentially permanent.

Indications of injection lipolysis include

  • Small, well-localized deposit of subcutaneous fat where a volume of 100 to 500 ml is considered ideal especially if soft, spongy fat eg. Face and arms.
  • Lipoma or multiple lipomas
  • Post liposuction deformities. Fat grafting if there is an area with too much “take” of the injected fat, or where the injected fat “take” unevenly is another indication for this procedure.
  • Kybella is an FDA approved treatment for “double chin”

How does the solution act?

  • It dissolves the fat by saponification.
  • Reduces the number of fat cells by lysing them.

Patient preparation

  • Topical Local anesthesia application.
  • Ice application until it is very cold.

Preparation of Solution

  • 1:1 ratio of the solution and normal saline
  • Load it the syringe
  • Inject in a grid pattern

Layer in which the solution has to be injected

  • Always subcutaneous layer

Important Points

  • Not to be injected in the muscle layer.
  • Injection into muscle causes myonecrosis.
  • Maximum effect in 80% patients is seen in 10 days.
  • Drug continuous to act for 6 to 8 weeks.
  • Minimum interval between each dosing – 4 weeks.


  • Myonecrosis
  • Fat atrophy
  • Ecchymosis
  • Erythema
  • Swelling and redness

Postoperative Care

  • Medications to bring down the swelling
  • Ice pack application to reduce the swelling
  • Postoperative review as suggested

Frequently Asked Questions

We like to assist our clients with a knowledgeable and in-depth collective approach to answer for all your queries and fears with our FAQ mega-base.

Not all types of Lipolysis are permanent. The most effective Lipolysis is the Injection Lipolysis which uses Phosphatidyl choline and Deoxycholate which is permanent if you do not put on weight. Other non surgical ways to reduce fat including Laser Lipolysis do not last long.

Usually 6- 8 sessions are needed along with a calorie restricted diet for a meaningful improvement of the area.

The results last till the person takes care of their diet and exercises and do not put on weight.

It is effective to a limited extent and is dependant on diet control and calorie burn out. All modes of Lipolysis only break the fat cell. They do not burn the fat. The liver is required to break this fat into fatty acids and excrete it. If the liver is not working well, the result is not appreciated.

A person who has a normal BMI, normal liver functions, has a stable weight, exercises and has a localised small resistant fat deposit is the ideal candidate.

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